Several online videos have surface of U.S. F-15 pilots ejecting out of aircraft that were seemingly hit during combat operations. According to most accounts the incidents took place over the skies of Kuwait and there are indications these were ‘friendly fire’ mistakes.
With all of the inbound drone, UAV, missile and ballistic missile activity it would not be a surprise to hear of Kuwaiti air defense forces accidentally targeting coalition or U.S. fighter jets that would be traversing the region.
All of the pilots are reported to be safe and with the assistance of the Kuwaiti government returning to their U.S. military bases. Given the “fog of war” it is best to wait until details are released from the Pentagon.

UPDATE: Immediately after writing, this update appears from CENTCOM:
TAMPA, Fla. – At 11:03 p.m. ET, March 1, three U.S. F-15E Strike Eagles flying in support of Operation Epic Fury went down over Kuwait due to an apparent friendly fire incident.
During active combat—that included attacks from Iranian aircraft, ballistic missiles, and drones — the U.S. Air Force fighter jets were mistakenly shot down by Kuwaiti air defenses.
All six aircrew ejected safely, have been safely recovered, and are in stable condition. Kuwait has acknowledged this incident, and we are grateful for the efforts of the Kuwaiti defense forces and their support in this ongoing operation.
The cause of the incident is under investigation. Additional information will be released as it becomes available. (SOURCE)
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